For bioanalytical methods for small molecule drugs in biological matrices, sample preparation is a critical step.   A balance must be achieved between a sample preparation method that reduces interferences while still being affordable and fast.    At Pine Lake Laboratories, we have successfully developed and validated a wide variety of bioanalytical methods that achieved this balance.   We have experience with mixed mode extraction, liquid-liquid extraction, solid phase extraction, protein precipitation and enzymatic digestion sample preparation methods.   We have the experience and expertise to develop the bioanalytical method needed to help advance your drug to the patients who need it.